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Sharpe (Timms) KL, Bertero MC, Lyon BP, Muse KN, Vernon MW. Follicular atresia and infertility in rats treated with a gonadotropin-releasing hormone antagonist. Endocrinol 1990 Jul;127(1):25-31 |
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Sharpe (Timms) KL, Bertero MC, Vernon MW. Spontaneous and steroid-induced recurrence of endometriosis following suppression by a gonadotropin‑releasing hormone antagonist in the rat. Amer J Obstet Gynecol 1991; 164:187-94. |
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Sharpe (Timms) KL, Zimmer RL, Khan RS, Penney LL. Proliferative and morphogenic changes induced by the co-culture of uterine and peritoneal cells: A cell culture model for endometriosis. Fertil Steril 1992; 58:1220-9. |
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Sharpe (Timms) KL, Vernon MW. Polypeptides synthesized and released by rat ectopic uterine tissue differ from those of the uterus in culture. Biol Reprod 1993; 48:1334-40. |
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Moon, CE, Bertero MB, Curry TE, London SN, Muse KN, Sharpe (Timms) KL, Vernon MW. The presence of luteinized unruptured follicle syndrome (LUFS) and altered folliculogenesis in rats with surgically induced endometriosis. Am J Ob Gyn 1993; 169:676- 82. |
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Sharpe (Timms) KL, Zimmer RL, Griffin WT, Penney LL. Polypeptides synthesized and released by human endometriosis tissue differ from those of the uterine endometrium in culture. Fertil Steril 1993; 60(5):839-51. |
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Wright JA and Sharpe-Timms KL. Gonadotropin-releasing hormone agonist (GnRHa) therapy reduces postoperative adhesion formation and reformation following adhesiolysis in rat models for adhesion formation and endometriosis. Fertil Steril 1995; 63:1094-100. |
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Sharpe-Timms KL, Penney LL, Zimmer RL, Wright JA, Zhang Y, Surewicz KS. Partial purification and amino acid sequence analysis of endometriosis protein-II (ENDO-II) reveals homology with tissue inhibitor of metalloproteinases-1 (TIMP-1). J Clin Endocrin Metab 1995; 80: 3784-7. |
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Sharpe-Timms KL, Piva M, Ricke EA, Surewicz K, Zhang YL, Zimmer RL. Endometriotic lesions synthesize and secrete a haptoglobin-like protein. Biol Reprod 1998; 58:988-94. |
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Sharpe-Timms KL, Keisler LW, McIntush EW, Keisler DH. Tissue inhibitor of metalloproteinase-1 (TIMP-1) concentrations are attenuated in peritoneal fluid and sera of women with endometriosis and restored in sera by gonadotropin-releasing hormone agonist (GnRHa) therapy. Fertil Steril 1998; 69(6): 1128-34. |
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Sharpe-Timms KL, Zimmer RL, Jolliff WJ, Wright JA, Nothnick WB, Curry TE. Gonadotropin-releasing hormone agonist (GnRHa) therapy alters activity of plasminogen activators (PA), matrix metalloproteinases (MMP) and of their inhibitors (PAI and MMPI) in rat models for adhesion formation and endometriosis: potential GnRHa-regulated mechanisms reducing adhesion formation. Fertil Steril 1998; 69(5):916-23. |
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Piva M, Sharpe-Timms KL. Peritoneal endometriotic lesions differentially express a haptoglobin-like gene. Molecular Human Reprod 1999; 5: (1):71-78. |
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Sharpe-Timms KL, Ricke EA, Piva M, Horowitz GM. Differential in vivo expression and localization of endometriosis protein-I (ENDO-I), a haptoglobin homologue, in endometrium and endometriotic lesions. Human Reproduction, 2000; 15(10):2180-5. |
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Cox KE, Sharpe-Timms KL, Kamiya N, Saraf M, Donnelly KM, Fazleabas AT. Differential regulation of stromelysin–1 (matrix metalloproteinase-3) and matrilysin (matrix metalloproteinase-7) in baboon endometrium. J Soc Gynecol Invest, 2000; 7:242-8. |
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Cox KE, Piva M, Sharpe-Timms KL. Differential regulation of matrix metalloproteinase-3 gene expression in endometriotic lesions as compared to endometrium. Biol Reprod 2001; 65: 1297-303. |
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Piva M, Horowitz GM, Sharpe-Timms KL. Interleukin-6 differentially stimulates haptoglobin production by peritoneal and endometriotic cells in vitro: a model for endometrium-peritoneum interaction in endometriosis. J Clin Endocrin Metab 2001; 86:2553-61. [Selected for publication in special June 2001 issue devoted, in part, to the theme of The Endocrine Society Annual Meeting, “Hormones and Reproductive Health.”] |
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Sharpe-Timms KL, Zimmer RL, Ricke EA, Piva MA, Horowitz GM. Endometriotic haptoglobin binds peritoneal macrophages and alters their function in endometriosis. Fertil Steril; 2002; 78:810-819. [Selected for Publication in Special Endometriosis Issue]. |
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Piva MA, Moreno I, Sharpe-Timms KL. Glycosylation and over-expression of endometriosis-associated peritoneal haptoglobin. Glycoconj J 2003; 19(1):33-41. |
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Sharpe-Timms KL, Young SL. Understanding Endometriosis: the key to successful therapeutic management. Fertil Steril 2004; 81(5): 1201-3 |
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Sutovsky P, Manandhar G, Laurincik J, Letko J, Caamano JN, Day BN, Lai L, Prather RS, Sharpe-Timms KL, Zimmer R, Sutovsky M. Expression and proteasomal degradation of the major vault protein (MVP) in mammalian oocytes and zygotes. Reproduction. 2005; 129(3):269-82:1-15. Selected for Cover Image. |
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Sharpe-Timms, KL. Haptoglobin expression by shed endometrial tissue fragments found in peritoneal fluid. Fertil Steril 2005; 84(1):22-30:35-7. |
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Sharpe-Timms, KL. Defining endometrial cells: the need for improved identification at ectopic sites and characterization in eutopic sites for developing novel methods of management for endometriosis. Fertil Steril 2005; 84(1):35-7; discussion 38-9:22-30. |
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Barrier BF, Kendall BS, Ryan CE, Sharpe-Timms KL. HLA-G is expressed by the glandular epithelium of peritoneal endometriosis but not in eutopic endometrium. Hum Reprod 2006 Apr; 21(4):864-9. Epub 2005 Nov 25. |
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Cameo P, Szmidt M, Strakova Z, Mavrogianis P, Sharpe-Timms KL, Fazleabas AT. Decidualization regulates the expression of the endometrial chorionic gonadotrophin receptor in the primate. Biol Reprod. 2006; 75:681-9 [Jul 12 Epub ahead of print] |
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Sharpe-Timms KL, Nabli H, Zimmer RL, Birt JA, Davis JW. Inflammatory cytokines upregulate human endometrial haptoglobin production providing insights into the pathogenesis and subfertility of endometriosis. Human Reproduction, submitted July 2008 |
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Sharpe-Timms KL, Zimmer RL, Nabli H. Endometriotic haptoglobin reduces macrophage phagocytic function endometriosis, favoring the establishment of endometriosis. Fertil Steril; in preparation. |
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Sharpe-Timms, KL, Marshall, R. Development of a novel comparative species microarray for translation of diagnostic data from an animal model to women with endometriosis. Biotechniques, in preparation |
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Stilley JA, Nabli H, Van Hook J, Zimmer, RL, Nabli H, Sharpe-Timms KL. Tissue inhibitor of metalloproteinase-1 (TIMP-1) secreted by endometriotic lesions contributes to the subfertility in endometriosis. Biol Reprod, in preparation |
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